There’s something undeniably crave-worthy about a rich, creamy pasta dish infused with bold Southern spices. That’s exactly what you’ll get with Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce. This recipe blends golden-seared Cajun chicken, tender linguine, and a garlicky Parmesan cream sauce for a weeknight meal that feels like a restaurant splurge. It’s warm, satisfying, and comes together with pantry staples—perfect for beginner cooks who want to impress without the stress.
Why You’ll Love This Creamy Cajun Chicken Spaghetti
Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce is more than just a pasta dish—it’s a cozy, flavorful experience. Here’s why you’ll love it:
- Deep Cajun Flavor: The seasoning brings warmth, depth, and a mild spicy kick.
- Creamy Garlic Sauce: A luscious mix of cream, garlic, and Parmesan coats every strand of pasta.
- Perfect Texture: The linguine soaks up the sauce beautifully while the chicken stays juicy and tender.
- Beginner-Friendly: With simple steps and a single skillet, this meal is easy to master.
The Story Behind Creamy Cajun Chicken Spaghetti
Here’s a taste of where this flavorful fusion comes from:
- Cajun Roots: Cajun seasoning is a Louisiana staple known for its smoky, bold flavor profile.
- Italian Flair: The Parmesan cream sauce nods to classic Alfredo—but with extra depth.
- Southern Comfort: It’s a warm, filling dish perfect for family dinners or chilly nights.
- Modern Twist: Combining Cajun spice with creamy pasta is a new Southern favorite.
Key Ingredients in Creamy Cajun Chicken Spaghetti
- Chicken Breasts – Lean and juicy, seasoned with bold Cajun spices.
- Cajun Seasoning – Adds that essential Southern heat and smoky depth.
- Linguine Pasta – A slightly thicker spaghetti that holds sauce like a pro.
- Heavy Cream – The base of your ultra-smooth, rich sauce.
- Grated Parmesan Cheese – Melts into the cream for savory, nutty flavor.
- Garlic – Sautéed in butter to infuse the whole sauce with warmth.
- Butter & Olive Oil – For cooking and building flavor in every layer.
- Chicken Broth – Adds umami and brings balance to the richness.
How to Make Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce
- Prep and Season the Chicken
Pat the chicken breasts dry with paper towels. Rub Cajun seasoning on both sides, pressing to help it stick. - Sear the Chicken
Heat 1 tbsp olive oil and 1 tbsp butter in a large skillet over medium-high heat. Cook chicken for 5–7 minutes per side until golden and cooked through. Transfer to a plate and cover loosely with foil. - Cook the Pasta
Bring salted water to a boil. Cook 1 lb linguine until al dente, per package instructions. Reserve 1/4 cup pasta water, then drain and set aside. - Make the Garlic Cream Sauce
In the same skillet, melt 4 tbsp butter over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. - Add Broth and Cream
Stir in chicken broth, scraping up any bits stuck to the pan. Pour in 1 cup heavy cream and bring to a gentle simmer. - Whisk in Parmesan
Reduce heat to low. Slowly whisk in 1/2 cup Parmesan until smooth. Season with salt and pepper. Add reserved pasta water to adjust thickness if needed. - Toss with Pasta
Add the cooked linguine to the sauce. Toss until fully coated and creamy. - Slice and Serve
Slice chicken into strips. Plate over the pasta, spoon over extra sauce, and garnish with parsley, basil, and more Parmesan if desired.
Creamy Cajun Chicken Spaghetti Tips and Twists
Tips:
- Use freshly grated Parmesan for the smoothest sauce.
- Reserve pasta water—it’s the secret to a silky finish.
- Don’t overcrowd the skillet when cooking chicken.
- Let chicken rest before slicing for juicier pieces.
- Adjust Cajun spice to your heat preference.
Variations:
- Swap Protein: Try shrimp, sausage, or even tofu for a twist.
- Add Veggies: Sautéed spinach or bell peppers make it heartier.
- Cheese Boost: Add a sprinkle of mozzarella or smoked gouda for richness.
Storage, Reheating, and Make-Ahead Tips
Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce stores and reheats like a dream.
- Storage: Refrigerate leftovers in an airtight container for up to 3 days.
- Reheating: Gently reheat on the stovetop or microwave, adding a splash of cream or broth to loosen the sauce.
- Make-Ahead: Cook chicken and sauce ahead of time; store separately and combine with freshly cooked pasta when ready to serve.
Serving Suggestions
Pair your spicy, creamy spaghetti with easy sides to round out the meal:
- Garlic Bread – Great for scooping up that luscious sauce.
- Roasted Broccoli – A simple veggie that balances the richness.
- Chilled Iced Tea – Refreshes the palate between bites.
- Side Salad – Toss mixed greens with vinaigrette for a crisp contrast.
- Lemon Wedges – A squeeze of citrus brightens every bite.
Frequently Asked Questions
Can I use a different pasta?
Yes! Fettuccine, penne, or spaghetti all work well.
Is this dish very spicy?
Not overly—mild to medium heat. Add more Cajun spice if you love heat.
Can I make it dairy-free?
Use dairy-free butter, cream, and Parmesan alternatives, but sauce texture may vary.
What if I don’t have Cajun seasoning?
Use a mix of paprika, garlic powder, onion powder, and cayenne.
Can I freeze it?
Not recommended—cream sauces tend to separate when frozen.
Enjoy Your Creamy Cajun Chicken Spaghetti
Now you’re ready to serve up Creamy Cajun Chicken Spaghetti with Garlic Mozzarella Sauce—a dreamy dish that hits every note: creamy, spicy, savory, and soul-warming. It’s the kind of meal that feels special but takes less than an hour from start to finish. Whether it’s a weeknight dinner or a crowd-pleasing dish for friends, this recipe belongs in your rotation. So grab your skillet, pour that cream, and let the Cajun magic begin!
Explore More Recipes You’ll Love
Looking to complete your meal or switch things up? Check out these tasty recipes from Abby’s Recipes:
- Roasted Broccoli and Carrots – A simple, oven-roasted veggie side that complements creamy pasta perfectly.
- Easy Spicy Chicken Sandwich – Carry that Cajun heat into your next lunch with this fiery favorite.
- Best Carrot Cake Cookies – For dessert, try these soft and spiced cookies that are perfect with tea or coffee.
- Simple Avocado Toast with Egg – A fresh, light breakfast idea for the next day.
Creamy Cajun Chicken Spaghetti with Mozzarella Sauce
Ingredients
For the Chicken:
- 4 boneless skinless chicken breasts (about 6 oz each)
- 2 tablespoons Cajun seasoning
- 1 tablespoon olive oil
- 1 tablespoon butter
For the Pasta:
- 1 pound linguine pasta
- 1/4 cup reserved pasta water
For the Sauce:
- 4 tablespoons butter
- 2 cloves garlic minced
- 1/2 cup chicken broth
- 1 1/4 cups heavy cream divided
- 1/2 cup grated Parmesan cheese plus extra for serving
- 1/4 teaspoon salt
- 1/4 teaspoon black pepper
- 1 tablespoon chopped fresh parsley for garnish
- 1/4 cup chopped fresh basil for garnish
Instructions
- Pat chicken breasts dry and season both sides with Cajun seasoning.
- Heat olive oil and 1 tbsp butter in a large skillet over medium-high. Sear chicken for 5–7 minutes per side until golden and cooked through. Remove and cover with foil.
- Cook linguine in salted boiling water until al dente. Reserve 1/4 cup of pasta water, then drain.
- In the same skillet, melt 4 tbsp butter over medium heat. Add garlic and sauté for 30 seconds.
- Stir in chicken broth, then add 1 cup heavy cream. Simmer on low for 3–4 minutes.
- Whisk in Parmesan cheese until smooth. Season with salt and pepper. Use reserved pasta water to thin sauce if needed.
- Add cooked linguine to the sauce and toss until coated.
- Slice chicken and serve over pasta. Top with extra sauce, parsley, basil, and Parmesan.
Notes
- Calories: 720 per serving (estimated),
- Protein: 42g,
- Carbohydrates: 50g,
- Fat: 40g,
- Saturated Fat: 20g,
- Sodium: 600mg,
- Fiber: 2g,
- Sugar: 2g